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cypX [2017-8-11 16:0:3]
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cypX [2017-8-11 16:0:3]

cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
Locus
BSU35060
Isoelectric point
5.31
Molecular weight
45.31 kDa
Protein length
405 aa Sequence Blast
Gene length
1215 bp Sequence Blast
Function
biosynthesis of the extracellular iron chelate pulcherrimin
Product
cytochrome P450, cyclo-l-leucyl-l-leucyl dipeptide oxidase
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Homeostasis → Acquisition of iron → Acquisition of iron / Other
  • Metabolism → Additional metabolic pathways → Iron metabolism → Acquisition of iron / Other

    • Gene

    Coordinates
    3,602,588 → 3,603,805

    The protein

    Catalyzed reaction/ biological activity

  • implicated in the three-step oxidative transformation of the diketopiperazine cyclo-l-leucyl-l-leucyl into pulcherriminic acid PubMed

    • Protein family

  • cytochrome P450 family (according to Swiss-Prot)

    • Structure

  • 3NC3 PubMed

    • Expression and Regulation

    Operons

    Genes
    yvmC-cypX
    Description
    Reference

    Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon
  • PchR: repression, in PchR regulon

    • Regulation

  • expression of the operon is strongly induced at the beginning of biofilm formation PubMed
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    Biological materials

    Mutant

  • MGNA-A333 (cypX::erm), available at the NBRP B. subtilis, Japan

    • References

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